Deadly coronavirus outbreak in Wuhan may have come from bats, research suggests

The genome sequence of the deadly virus sweeping across China is 96% identical to a bat coronavirus, according to a Nature study. China’s Health Commission reported on Sunday that there have been 361 deaths nationwide.

Bats are the potential source of coronavirus, new research suggests.

However, scientists stress the animal source of the recent outbreak in China has not been confirmed.

China’s Health Commission reported on Sunday that there have been 361 deaths nationwide.

Identification and characterisation of the new virus reveals similarities with severe acute respiratory syndrome (Sars) coronaviruses.

Researchers analysed samples from seven patients with severe pneumonia, six of whom were identified as workers from the seafood market in Wuhan.

They found that full-length genome sequences – which determined the DNA of the virus – from five of the patients were almost (over 99.9%) identical to each other.

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They also shared 79.5% sequence identity with Sars coronaviruses.

According to the study published in Nature, the virus sequence is 96% identical to a bat coronavirus, suggesting bats are a probable source of this coronavirus.

Reports suggest no bats were sold at the seafood market where the outbreak is believed to have originated.

This indicates the virus may have spread through another animal – yet to be identified – acting as an intermediate host between bats and humans.

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Diana Bell, Professor of conservation biology at the University of East Anglia, said she is not convinced bats are to blame.

She told the PA news agency that information she received suggested there were no bats in the market and that at this time of year they would not be flying around.

Prof Bell explained that it was dangerous to point the finger at bats and stop looking for alternative sources, without having looked at all other possible sources.

She said: "I will only be convinced that bats are the source once other factors have also been extensively studied.

"I think it is important to keep an open mind."

The virus can spread from humans coming into contact with infected animals.

It is unlikely to survive in animals that have died, experts say.

Scientists also found the new virus, named 2019-nCoV, enters cells through the same route as Sars coronaviruses.

Antibodies isolated from patients infected with the new strain are shown to have the potential to neutralise the virus.

Zheng-Li Shi, a virologist and researcher at the Wuhan Institute of Virology, and colleagues developed a test that can differentiate 2019-nCoV from all other human coronaviruses.

They found that while it was detected in initial oral swab samples, subsequent samples taken about 10 days later did not have a positive viral result.

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This suggests the most likely route of transmission is through the airways of individuals.

Dr Michael Skinner, reader in virology at Imperial College London, said: "The discovery definitely places the origin of nCoV in bats in China.

"We still do not know whether another species served as an intermediate host to amplify the virus, and possibly even to bring it to the market, nor what species that host might have been."

In a separate study, researchers studied a 41-year-old male market worker admitted to a hospital in Wuhan on December 26 2019, who experienced symptoms of respiratory illness, including fever, chest tightness and a cough.

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In a sample of fluid taken from his lung, they identified a novel virus and found that the viral genome shared 89.1% similarity with Sars-like coronaviruses from bats.

But the researchers say it is not possible to conclude from the analysis of a single patient that this coronavirus is the cause of the current outbreak.

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host”,”relevance”:0.547957},{“count”:1,”text”:”DNA of the virus”,”relevance”:0.541172},{“count”:1,”text”:”new research”,”relevance”:0.540523},{“count”:1,”text”:”sample of fluid”,”relevance”:0.538561},{“count”:1,”text”:”novel virus”,”relevance”:0.537927},{“count”:1,”text”:”animal source of the recent outbreak”,”relevance”:0.537243},{“count”:1,”text”:”possible sources”,”relevance”:0.536793}],”analyzed_text”:”The genome sequence of the deadly virus sweeping across China is 96% identical to a bat coronavirus, according to a Nature study. China’s Health Commission reported on Sunday that there have been 361 deaths nationwide.nBats are the potential source of coronavirus, new research suggests.nHowever, scientists stress the animal source of the recent outbreak in China has not been confirmed.nChina’s Health Commission reported on Sunday that there have been 361 deaths nationwide.nIdentification and characterisation of the new virus reveals similarities with severe acute respiratory syndrome (Sars) coronaviruses.nResearchers analysed samples from seven patients with severe pneumonia, six of whom were identified as workers from the seafood market in Wuhan.nThey found that full-length genome sequences – which determined the DNA of the virus – from five of the patients were almost (over 99.9%) identical to each other.nBaby boy born inside coronavirus quarantine while midwives wear hazmat suits nBrits trapped in coronavirus epicentre are warned about ‘last flights’ outnThey also shared 79.5% sequence identity with Sars coronaviruses.nAccording to the study published in Nature, the virus sequence is 96% identical to a bat coronavirus, suggesting bats are a probable source of this coronavirus.nReports suggest no bats were sold at the seafood market where the outbreak is believed to have originated.nThis indicates the virus may have spread through another animal – yet to be identified – acting as an intermediate host between bats and humans.nDoctor who predicted coronavirus days before epidemic hit arrested in raid on homenDiana Bell, Professor of conservation biology at the University of East Anglia, said she is not convinced bats are to blame.nShe told the PA news agency that information she received suggested there were no bats in the market and that at this time of year they would not be flying around.nProf Bell explained that it was dangerous to point the finger at bats and stop looking for alternative sources, without having looked at all other possible sources.nShe said: “I will only be convinced that bats are the source once other factors have also been extensively studied.n”I think it is important to keep an open mind.”nThe virus can spread from humans coming into contact with infected animals. nIt is unlikely to survive in animals that have died, experts say.nScientists also found the new virus, named 2019-nCoV, enters cells through the same route as Sars coronaviruses.nAntibodies isolated from patients infected with the new strain are shown to have the potential to neutralise the virus.nZheng-Li Shi, a virologist and researcher at the Wuhan Institute of Virology, and colleagues developed a test that can differentiate 2019-nCoV from all other human coronaviruses. nThey found that while it was detected in initial oral swab samples, subsequent samples taken about 10 days later did not have a positive viral result.nBritish coronavirus evacuee is rushed to hospital after being ‘taken ill’ in UKnThis suggests the most likely route of transmission is through the airways of individuals.nDr Michael Skinner, reader in virology at Imperial College London, said: “The discovery definitely places the origin of nCoV in bats in China. n”We still do not know whether another species served as an intermediate host to amplify the virus, and possibly even to bring it to the market, nor what species that host might have been.”nIn a separate study, researchers studied a 41-year-old male market worker admitted to a hospital in Wuhan on December 26 2019, who experienced symptoms of respiratory illness, including fever, chest tightness and a cough.n Coronavirus outbreak nIn a sample of fluid taken from his lung, they identified a novel virus and found that the viral genome shared 89.1% similarity with Sars-like coronaviruses from bats.nBut the researchers say it is not possible to conclude from the analysis of a single patient that this coronavirus is the cause of the current 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Coronavirus

NewsDeadly coronavirus outbreak in Wuhan may have come from bats, research suggests

Bats are the potential source of coronavirus, new research suggests.

However, scientists stress the animal source of the recent outbreak in China has not been confirmed.

China’s Health Commission reported on Sunday that there have been 361 deaths nationwide.

Identification and characterisation of the new virus reveals similarities with severe acute respiratory syndrome (Sars) coronaviruses.

Researchers analysed samples from seven patients with severe pneumonia, six of whom were identified as workers from the seafood market in Wuhan.

They found that full-length genome sequences – which determined the DNA of the virus – from five of the patients were almost (over 99.9%) identical to each other.

The virus was found to be 96% identical to a bat coronavirus
(Image: Getty Images/iStockphoto)

Baby boy born inside coronavirus quarantine while midwives wear hazmat suits

Brits trapped in coronavirus epicentre are warned about 'last flights' out

They also shared 79.5% sequence identity with Sars coronaviruses.

According to the study published in Nature, the virus sequence is 96% identical to a bat coronavirus, suggesting bats are a probable source of this coronavirus.

Reports suggest no bats were sold at the seafood market where the outbreak is believed to have originated.

This indicates the virus may have spread through another animal – yet to be identified – acting as an intermediate host between bats and humans.

Exhausted Chinese doctors are sleeping on the floors of hospitals as they fight the virus
(Image: AsiaWire/Weibo)

Doctor who predicted coronavirus days before epidemic hit arrested in raid on home

Diana Bell, Professor of conservation biology at the University of East Anglia, said she is not convinced bats are to blame.

She told the PA news agency that information she received suggested there were no bats in the market and that at this time of year they would not be flying around.

Prof Bell explained that it was dangerous to point the finger at bats and stop looking for alternative sources, without having looked at all other possible sources.

A girl wears a mask as she walks past a scanning machine monitoring people's temperature in Sri Lanka
(Image: REUTERS)

She said: "I will only be convinced that bats are the source once other factors have also been extensively studied.

"I think it is important to keep an open mind."

The virus can spread from humans coming into contact with infected animals.

It is unlikely to survive in animals that have died, experts say.

Medical staff in protective suits treat a patient with pneumonia caused by the new coronavirus
(Image: REUTERS)

Scientists also found the new virus, named 2019-nCoV, enters cells through the same route as Sars coronaviruses.

Antibodies isolated from patients infected with the new strain are shown to have the potential to neutralise the virus.

Zheng-Li Shi, a virologist and researcher at the Wuhan Institute of Virology, and colleagues developed a test that can differentiate 2019-nCoV from all other human coronaviruses.

They found that while it was detected in initial oral swab samples, subsequent samples taken about 10 days later did not have a positive viral result.

Medical staff queue in line to register for the medical workers strike in Hong Kong
(Image: Anadolu Agency via Getty Images)

Security personnel wearing hazardous material suits wait to measure body temperatures at the subway
(Image: WU HONG/EPA-EFE/REX)

British coronavirus evacuee is rushed to hospital after being 'taken ill' in UK

This suggests the most likely route of transmission is through the airways of individuals.

Dr Michael Skinner, reader in virology at Imperial College London, said: "The discovery definitely places the origin of nCoV in bats in China.

"We still do not know whether another species served as an intermediate host to amplify the virus, and possibly even to bring it to the market, nor what species that host might have been."

In a sample of fluid taken from his lung, they identified a novel virus and found that the viral genome shared 89.1% similarity with Sars-like coronaviruses from bats.

But the researchers say it is not possible to conclude from the analysis of a single patient that this coronavirus is the cause of the current outbreak.

Sourse: www.mirror.co.uk

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